Biotech Manufacturing Companies in South Carolina

South Carolina has approximately 4,500 manufacturing establishments and 260,000 manufacturing employees. South Carolina is a booming automotive and aerospace state, with BMW's largest plant in Spartanburg, Boeing's 787 line in Charleston, and Volvo's assembly plant in Ridgeville.

South Carolina contributes to the national biotech manufacturing landscape. Biotech manufacturing encompasses the production of biologic drugs including monoclonal antibodies, cell and gene therapies, vaccines, and recombinant proteins. Unlike traditional pharmaceutical manufacturing, biotech production relies on living cell systems and requires specialized bioprocessing equipment, single-use systems, and advanced purification technologies.

Monoclonal Antibody Producers: Companies operating large-scale mammalian cell culture facilities for antibody drug production.

Cell Therapy Manufacturers: Facilities producing autologous and allogeneic cell therapies including CAR-T and stem cell products.

Gene Therapy Producers: Companies manufacturing viral vectors (AAV, lentivirus) for gene therapy applications.

Vaccine Manufacturers: Facilities producing vaccines using traditional and mRNA platforms, including fill-finish operations.

Contract Biologics Manufacturers: CDMOs specializing in biologic drug manufacturing, from cell line development through commercial production.

Major industrial centers in South Carolina include Charleston, Greenville, Columbia, Spartanburg, and Greer. These cities have concentrations of manufacturers across sectors including automotive oem manufacturing, aerospace manufacturing, and automotive tier 1 suppliers.