Biotech Manufacturing Companies in Missouri

Missouri has approximately 5,500 manufacturing establishments and 270,000 manufacturing employees. Missouri is a major aerospace state, home to Boeing's defense operations in St. Louis, with additional strength in automotive assembly and food processing.

Missouri contributes to the national biotech manufacturing landscape. Biotech manufacturing encompasses the production of biologic drugs including monoclonal antibodies, cell and gene therapies, vaccines, and recombinant proteins. Unlike traditional pharmaceutical manufacturing, biotech production relies on living cell systems and requires specialized bioprocessing equipment, single-use systems, and advanced purification technologies.

Monoclonal Antibody Producers: Companies operating large-scale mammalian cell culture facilities for antibody drug production.

Cell Therapy Manufacturers: Facilities producing autologous and allogeneic cell therapies including CAR-T and stem cell products.

Gene Therapy Producers: Companies manufacturing viral vectors (AAV, lentivirus) for gene therapy applications.

Vaccine Manufacturers: Facilities producing vaccines using traditional and mRNA platforms, including fill-finish operations.

Contract Biologics Manufacturers: CDMOs specializing in biologic drug manufacturing, from cell line development through commercial production.

Major industrial centers in Missouri include St. Louis, Kansas City, Springfield, Columbia, and Joplin. These cities have concentrations of manufacturers across sectors including aerospace manufacturing, automotive oem manufacturing, and food processing manufacturing.