Pharmaceutical Manufacturing Companies in South Dakota

South Dakota has approximately 900 manufacturing establishments and 46,000 manufacturing employees. South Dakota's manufacturing sector is led by food processing operations in Sioux Falls, with additional strength in metal fabrication and agricultural equipment.

South Dakota contributes to the national pharmaceutical manufacturing landscape. Pharmaceutical manufacturing includes companies that produce prescription drugs, over-the-counter medications, generic drugs, and active pharmaceutical ingredients (APIs). The US pharmaceutical industry spans large-scale continuous process manufacturing of solid dosage forms to sterile fill-finish operations for injectables and biologics.

Solid Dosage Manufacturers: Companies producing tablets, capsules, and oral solid dosage forms using granulation, compression, and coating equipment.

Sterile Fill-Finish Operations: Facilities performing aseptic filling of vials, syringes, and IV bags in cleanroom environments.

API Manufacturers: Chemical manufacturing plants producing active pharmaceutical ingredients through synthesis and purification processes.

CDMOs: Contract development and manufacturing organizations providing drug manufacturing services to pharma companies.

Packaging & Labeling Operations: Companies providing pharmaceutical packaging, serialization, and labeling in compliance with FDA track-and-trace requirements.

Major industrial centers in South Dakota include Sioux Falls, Rapid City, and Aberdeen. These cities have concentrations of manufacturers across sectors including food processing manufacturing, metal fabrication, and agricultural equipment manufacturing.